Articles by Author

Abbott DE, Pritchard C, Clegg NJ, Ferguson C, Dumpit R, Sikes RA, Nelson PS.  Expressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostate. Genome Biol. 2003;4(12):R79. Epub 2003 Nov 28. PubMed PMID: 14659016.

Aigner A, Renneberg H, Bojunga J, Apel J, Nelson PS, Czubayko F. Ribozyme-targeting of a secreted FGF-binding protein (FGF-BP) inhibits proliferation of prostate cancer cells in vitro and in vivo. Oncogene. 2002 Aug 22;21(37):5733-42. PubMed PMID: 12173043.

Akalin A, Elmore LW, Forsythe HL, Amaker BA, McCollum ED, Nelson PS, Ware JL, Holt SE. A novel mechanism for chaperone-mediated telomerase regulation during prostate cancer progression. Cancer Res. 2001 Jun 15;61(12):4791-6. PubMed PMID:  11406554.

Arnold RS, Sun CQ, Richards JC, Grigoriev G, Coleman IM, Nelson PS, Hsieh CL,  Lee JK, Xu Z, Rogatko A, Osunkoya AO, Zayzafoon M, Chung L, Petros JA. Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment. Prostate. 2009 Jan 1;69(1):1-11. PubMed PMID: 18850577.

Bavik C, Coleman I, Dean JP, Knudsen B, Plymate S, Nelson PS. The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms. Cancer Res. 2006 Jan  15;66(2):794-802. PubMed PMID: 16424011.

Belyaeva OV, Korkina OV, Stetsenko AV, Kim T, Nelson PS, Kedishvili NY. Biochemical properties of purified human retinol dehydrogenase 12 (RDH12): catalytic efficiency toward retinoids and C9 aldehydes and effects of cellular retinol-binding protein type I (CRBPI) and cellular retinaldehyde-binding protein (CRALBP) on the oxidation and reduction of retinoids. Biochemistry. 2005 May 10;44(18):7035-47. PubMed PMID: 15865448.

Bhattacharjee M, Pritchard CC, Nelson PS, Arjas E. Bayesian integrated functional analysis of microarray data. Bioinformatics. 2004 Nov 22;20(17):2943-53. Epub 2004 Jun 4. PubMed PMID: 15180937.

Bianchi-Frias D, Pritchard C, Mecham BH, Coleman IM, Nelson PS. Genetic background influences murine prostate gene expression: implications for cancer phenotypes. Genome Biol. 2007;8(6):R117. PubMed PMID: 17577413.

Bluemn EG, Paulson KG, Higgins EE, Sun Y, Nghiem P, Nelson PS. Merkel cell polyomavirus is not detected in prostate cancers, surrounding stroma, or benign prostate controls. J Clin Virol. 2009 Feb;44(2):164-6. Epub 2009 Jan 6. PubMed PMID: 19129009.

Bonham M, Arnold H, Montgomery B, Nelson PS. Molecular effects of the herbal  compound PC-SPES: identification of activity pathways in prostate carcinoma. Cancer Res. 2002 Jul 15;62(14):3920-4. PubMed PMID: 12124319.

Bonham M, Posakony J, Coleman I, Montgomery B, Simon J, Nelson PS. Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. Clin Cancer Res. 2005 May 15;11(10):3905-14. PubMed PMID: 15897592.

Bonham MJ, Galkin A, Montgomery B, Stahl WL, Agus D, Nelson PS. Effects of the herbal extract PC-SPES on microtubule dynamics and paclitaxel-mediated prostate tumor growth inhibition. J Natl Cancer Inst. 2002 Nov 6;94(21):1641-7. PubMed PMID: 12419791.

Carroll PR, Chan JM, D’Amico AV, Gelmann EP, Iversen P, Klotz L, Nelson JB, Nelson PS, Nelson WG, Oh WK, Rosen N, Rubin MA, Sandler H, Sellers WR, Smith MR,  Xu J, McMann MC, Kantoff PW. Fourth International Conference on Innovations and Challenges in Prostate Cancer: Prevention, Detection and Treatment. J Urol. 2004  Nov;172(5 Pt 2):S3-5. Review. PubMed PMID: 15535434.

Chaudhary PM, Ferguson C, Nguyen V, Nguyen O, Massa HF, Eby M, Jasmin A, Trask BJ, Hood L, Nelson PS. Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans. Blood. 1998 Jun 1;91(11):4020-7. PubMed PMID: 9596645.

Chen Q, Watson JT, Marengo SR, Decker KS, Coleman I, Nelson PS, Sikes RA. Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with  prostate cancer progression in vivo. Cancer Lett. 2006 Dec 8;244(2):274-88. Epub  2006 Feb 23. PubMed PMID: 16500022.

Clegg N, Abbott D, Ferguson C, Coleman R, Nelson PS. Characterization and comparative analyses of transcriptomes from the normal and neoplastic human prostate. Prostate. 2004 Aug 1;60(3):227-39. PubMed PMID: 15176052.

Clegg N, Eroglu B, Ferguson C, Arnold H, Moorman A, Nelson PS. Digital expression profiles of the prostate androgen-response program. J Steroid Biochem  Mol Biol. 2002 Jan;80(1):13-23. PubMed PMID: 11867260.

Clegg N, Ferguson C, True LD, Arnold H, Moorman A, Quinn JE, Vessella RL, Nelson PS. Molecular characterization of prostatic small-cell neuroendocrine carcinoma. Prostate. 2003 Apr 1;55(1):55-64. PubMed PMID: 12640661.

Coleman IM, Kiefer JA, Brown LG, Pitts TE, Nelson PS, Brubaker KD, Vessella RL, Corey E. Inhibition of androgen-independent prostate cancer by estrogenic compounds is associated with increased expression of immune-related genes. Neoplasia. 2006 Oct;8(10):862-78. PubMed PMID: 17032503.

Coppé JP, Patil CK, Rodier F, Sun Y, Muñoz DP, Goldstein J, Nelson PS, Desprez PY, Campisi J. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS  Biol. 2008 Dec 2;6(12):2853-68. PubMed PMID: 19053174.

Corey E, Quinn JE, Buhler KR, Nelson PS, Macoska JA, True LD, Vessella RL. LuCaP 35: a new model of prostate cancer progression to androgen independence. Prostate. 2003 Jun 1;55(4):239-46. PubMed PMID: 12712403.

Corthals GL, Nelson PS. Large-scale proteomics and its future impact on medicine. Pharmacogenomics J. 2001;1(1):15-9. PubMed PMID: 11913721.

Datta MW, True LD, Nelson PS, Amin MB. The role of tissue microarrays in prostate cancer biomarker discovery. Adv Anat Pathol. 2007 Nov;14(6):408-18. Review. PubMed PMID: 18049130.

Dean JP, Nelson PS. Profiling influences of senescent and aged fibroblasts on prostate carcinogenesis. Br J Cancer. 2008 Jan 29;98(2):245-9. Epub 2008 Jan 8. Review. PubMed PMID: 18182995.

Diamandis EP, Yousef GM, Clements J, Ashworth LK, Yoshida S, Egelrud T, Nelson PS, Shiosaka S, Little S, Lilja H, Stenman UH, Rittenhouse HG, Wain H. New nomenclature for the human tissue kallikrein gene family. Clin Chem. 2000 Nov;46(11):1855-8. PubMed PMID: 11067830.

Drivdahl R, Haugk KH, Sprenger CC, Nelson PS, Tennant MK, Plymate SR. Suppression of growth and tumorigenicity in the prostate tumor cell line M12 by overexpression of the transcription factor SOX9. Oncogene. 2004 Jun 3;23(26):4584-93. PubMed PMID: 15077158.

Fraser MM, Watson PM, Fraig MM, Kelley JR, Nelson PS, Boylan AM, Cole DJ, Watson DK. CaSm-mediated cellular transformation is associated with altered gene  expression and messenger RNA stability. Cancer Res. 2005 Jul 15;65(14):6228-36. PubMed PMID: 16024624.

Grouse LH, Munson PJ, Nelson PS. Sequence databases and microarrays as tools  for identifying prostate cancer biomarkers. Urology. 2001 Apr;57(4 Suppl 1):154-9. Review. PubMed PMID: 11295616.

Haeseleer F, Jang GF, Imanishi Y, Driessen CA, Matsumura M, Nelson PS, Palczewski K. Dual-substrate specificity short chain retinol dehydrogenases from  the vertebrate retina. J Biol Chem. 2002 Nov 22;277(47):45537-46. Epub 2002 Sep 10. PubMed PMID: 12226107.

Harris WP, Mostaghel EA, Nelson PS, Montgomery B; Medscape. Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion. Nat Clin Pract Urol. 2009 Feb;6(2):76-85. PubMed PMID: 19198621.

Hawkins V, Doll D, Bumgarner R, Smith T, Abajian C, Hood L, Nelson PS. PEDB: the Prostate Expression Database. Nucleic Acids Res. 1999 Jan 1;27(1):204-8. PubMed PMID: 9847181.

He Y, Franco OE, Jiang M, Williams K, Love HD, Coleman IM, Nelson PS, Hayward SW. Tissue-specific consequences of cyclin D1 overexpression in prostate cancer progression. Cancer Res. 2007 Sep 1;67(17):8188-97. PubMed PMID: 17804732.

Holcomb IN, Grove DI, Kinnunen M, Friedman CL, Gallaher IS, Morgan TM, Sather CL, Delrow JJ, Nelson PS, Lange PH, Ellis WJ, True LD, Young JM, Hsu L, Trask BJ, Vessella RL. Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate cancer patients. Cancer Res. 2008 Jul 15;68(14):5599-608. PubMed PMID: 18632612.

Holt SK, Karyadi DM, Kwon EM, Stanford JL, Nelson PS, Ostrander EA. Association of megalin genetic polymorphisms with prostate cancer risk and prognosis. Clin Cancer Res. 2008 Jun 15;14(12):3823-31. PubMed PMID: 18559602.

Huang CY, Beer TM, Higano CS, True LD, Vessella R, Lange PH, Garzotto M, Nelson PS. Molecular alterations in prostate carcinomas that associate with in vivo exposure to chemotherapy: identification of a cytoprotective mechanism involving growth differentiation factor 15. Clin Cancer Res. 2007 Oct 1;13(19):5825-33. PubMed PMID: 17908975.

Kalhorn TF, Page ST, Howald WN, Mostaghel EA, Nelson PS. Analysis of testosterone and dihydrotestosterone from biological fluids as the oxime derivatives using high-performance liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2007;21(19):3200-6. PubMed PMID: 17764104.

Kedishvili NY, Chumakova OV, Chetyrkin SV, Belyaeva OV, Lapshina EA, Lin DW,  Matsumura M, Nelson PS. Evidence that the human gene for prostate short-chain dehydrogenase/reductase (PSDR1) encodes a novel retinal reductase (RalR1). J Biol Chem. 2002 Aug 9;277(32):28909-15. Epub 2002 May 29. PubMed PMID: 12036956.

Khodavirdi AC, Song Z, Yang S, Zhong C, Wang S, Wu H, Pritchard C, Nelson PS, Roy-Burman P. Increased expression of osteopontin contributes to the progression  of prostate cancer. Cancer Res. 2006 Jan 15;66(2):883-8. PubMed PMID: 16424021.

Kim TS, Heinlein C, Hackman RC, Nelson PS. Phenotypic analysis of mice lacking the Tmprss2-encoded protease. Mol Cell Biol. 2006 Feb;26(3):965-75. PubMed PMID: 16428450.

Kim TS, Maeda A, Maeda T, Heinlein C, Kedishvili N, Palczewski K, Nelson PS.  Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: a role of RDH11 in visual processes in vivo. J Biol Chem. 2005 Mar 11;280(10):8694-704. Epub 2005 Jan 4. PubMed PMID: 15634683.

Kinoshita Y, Jarell AD, Flaman JM, Foltz G, Schuster J, Sopher BL, Irvin DK,  Kanning K, Kornblum HI, Nelson PS, Hieter P, Morrison RS. Pescadillo, a novel cell cycle regulatory protein abnormally expressed in malignant cells. J Biol Chem. 2001 Mar 2;276(9):6656-65. Epub 2000 Nov 8. PubMed PMID: 11071894.

Klezovitch O, Risk M, Coleman I, Lucas JM, Null M, True LD, Nelson PS, Vasioukhin V. A causal role for ERG in neoplastic transformation of prostate epithelium. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2105-10. Epub 2008 Feb 1. PubMed PMID: 18245377.

Knudsen BS, Lucas JM, Fazli L, Hawley S, Falcon S, Coleman IM, Martin DB, Xu  C, True LD, Gleave ME, Nelson PS, Ayala GE. Regulation of hepatocyte activator inhibitor-1 expression by androgen and oncogenic transformation in the prostate.  Am J Pathol. 2005 Jul;167(1):255-66. PubMed PMID: 15972969.

Li PE, Nelson PS. Prostate cancer genomics. Curr Urol Rep. 2001 Feb;2(1):70-8. Review. PubMed PMID: 12084298.

Lin B, Ferguson C, White JT, Wang S, Vessella R, True LD, Hood L, Nelson PS. Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. Cancer Res. 1999 Sep 1;59(17):4180-4. PubMed PMID: 10485450.

Lin B, Utleg AG, Gravdal K, White JT, Halvorsen OJ, Lu W, True LD, Vessella R, Lange PH, Nelson PS, Hood L, Kalland KH, Akslen LA. WDR19 expression is increased in prostate cancer compared with normal cells, but low-intensity expression in cancers is associated with shorter time to biochemical failures and local recurrence. Clin Cancer Res. 2008 Mar 1;14(5):1397-406. PubMed PMID: 18316561.

Lin B, White JT, Ferguson C, Bumgarner R, Friedman C, Trask B, Ellis W, Lange P, Hood L, Nelson PS. PART-1: a novel human prostate-specific, androgen-regulated gene that maps to chromosome 5q12. Cancer Res. 2000 Feb 15;60(4):858-63. PubMed PMID: 10706094.

Lin B, White JT, Ferguson C, Wang S, Vessella R, Bumgarner R, True LD, Hood L, Nelson PS. Prostate short-chain dehydrogenase reductase 1 (PSDR1): a new member of the short-chain steroid dehydrogenase/reductase family highly expressed in normal and neoplastic prostate epithelium. Cancer Res. 2001 Feb 15;61(4):1611-8. PubMed PMID: 11245473.

Lin B, White JT, Utleg AG, Wang S, Ferguson C, True LD, Vessella R, Hood L, Nelson PS. Isolation and characterization of human and mouse WDR19,a novel WD-repeat protein exhibiting androgen-regulated expression in prostate epithelium. Genomics. 2003 Sep;82(3):331-42. PubMed PMID: 12906858.

Lin DW, Coleman IM, Hawley S, Huang CY, Dumpit R, Gifford D, Kezele P, Hung H, Knudsen BS, Kristal AR, Nelson PS. Influence of surgical manipulation on prostate gene expression: implications for molecular correlates of treatment effects and disease prognosis. J Clin Oncol. 2006 Aug 10;24(23):3763-70. Epub 2006 Jul 5. Erratum in: J Clin Oncol. 2007 Jun 1;25(16):2334. Huang, Chung Y [added]. PubMed PMID: 16822846.

Lin DW, Nelson PS. Microarray analysis and tumor classification. N Engl J Med. 2006 Aug 31;355(9):960; author reply 960. PubMed PMID: 16943413.

Lin DW, Nelson PS. The role of cyclooxygenase-2 inhibition for the prevention and treatment of prostate carcinoma. Clin Prostate Cancer. 2003 Sep;2(2):119-26.  PubMed PMID: 15040874.

Lin DW, Neuhouser ML, Schenk JM, Coleman IM, Hawley S, Gifford D, Hung H, Knudsen BS, Nelson PS, Kristal AR. Low-fat, low-glycemic load diet and gene expression in human prostate epithelium: a feasibility study of using cDNA microarrays to assess the response to dietary intervention in target tissues. Cancer Epidemiol Biomarkers Prev. 2007 Oct;16(10):2150-4. PubMed PMID: 17932364.

Liu AY, Corey E, Vessella RL, Lange PH, True LD, Huang GM, Nelson PS, Hood L. Identification of differentially expressed prostate genes: increased expression of transcription factor ETS-2 in prostate cancer. Prostate. 1997 Feb 15;30(3):145-53. PubMed PMID: 9122038.

Liu AY, Nelson PS, van den Engh G, Hood L. Human prostate epithelial cell-type cDNA libraries and prostate expression patterns. Prostate. 2002 Feb 1;50(2):92-103. PubMed PMID: 11816017.

Liu AY, True LD, LaTray L, Nelson PS, Ellis WJ, Vessella RL, Lange PH, Hood  L, van den Engh G. Cell-cell interaction in prostate gene regulation and cytodifferentiation. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10705-10. PubMed PMID: 9380699.

Lu W, Zhou D, Glusman G, Utleg AG, White JT, Nelson PS, Vasicek TJ, Hood L, Lin B. KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that is expressed at lower levels in prostate cancer cells than in normal prostate cells. Prostate. 2006 Jun 15;66(9):936-44. PubMed PMID: 16541416.

Lucas JM, True L, Hawley S, Matsumura M, Morrissey C, Vessella R, Nelson PS.  The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma. J Pathol. 2008 Jun;215(2):118-25. PubMed PMID: 18338334.

Marks LS, Mazer NA, Mostaghel E, Hess DL, Dorey FJ, Epstein JI, Veltri RW, Makarov DV, Partin AW, Bostwick DG, Macairan ML, Nelson PS. Effect of testosterone replacement therapy on prostate tissue in men with late-onset hypogonadism: a randomized controlled trial. JAMA. 2006 Nov 15;296(19):2351-61. PubMed PMID: 17105798.

Marks LS, Mostaghel EA, Nelson PS. Prostate tissue androgens: history and current clinical relevance. Urology. 2008 Aug;72(2):247-54. Epub 2008 May 27. Review. PubMed PMID: 18502483.

Martin DB, Gifford DR, Wright ME, Keller A, Yi E, Goodlett DR, Aebersold R, Nelson PS. Quantitative proteomic analysis of proteins released by neoplastic prostate epithelium. Cancer Res. 2004 Jan 1;64(1):347-55. PubMed PMID: 14729644.

Martin DB, Nelson PS. From genomics to proteomics: techniques and applications in cancer research. Trends Cell Biol. 2001 Nov;11(11):S60-5. Review. PubMed PMID: 11684444.

Matsumura M, Bhatt AS, Andress D, Clegg N, Takayama TK, Craik CS, Nelson PS.  Substrates of the prostate-specific serine protease prostase/KLK4 defined by positional-scanning peptide libraries. Prostate. 2005 Jan 1;62(1):1-13. PubMed PMID: 15389820.

Mendiratta P, Mostaghel E, Guinney J, Tewari AK, Porrello A, Barry WT, Nelson  PS, Febbo PG. Genomic strategy for targeting therapy in castration-resistant prostate cancer. J Clin Oncol. 2009 Apr 20;27(12):2022-9. Epub 2009 Mar 16. PubMed PMID: 19289629.

Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, Peterson A, Noteboom J, O’Briant KC, Allen A, Lin DW, Urban N, Drescher CW, Knudsen BS, Stirewalt DL, Gentleman R, Vessella RL, Nelson PS, Martin DB, Tewari  M. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10513-8. Epub 2008 Jul 28. PubMed PMID:  18663219.

Montgomery RB, Bonham M, Nelson PS, Grim J, Makary E, Vessella R, Stahl WL. Estrogen effects on tubulin expression and taxane mediated cytotoxicity in prostate cancer cells. Prostate. 2005 Oct 1;65(2):141-50. PubMed PMID: 15924336.

Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, Higano CS, True LD, Nelson PS. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res. 2008 Jun 1;68(11):4447-54. PubMed PMID: 18519708.

Montgomery RB, Nelson PS, Lin D, Ryan CW, Garzotto M, Beer TM. Diethylstilbestrol and docetaxel: a Phase II study of tubulin active agents in patients with metastatic, androgen-independent prostate cancer. Cancer. 2007 Sep  1;110(5):996-1002. PubMed PMID: 17639587.

Moore S, Knudsen B, True LD, Hawley S, Etzioni R, Wade C, Gifford D, Coleman  I, Nelson PS. Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma. Int J Cancer. 2005 Apr 20;114(4):563-71. PubMed PMID: 15609334.

Moore S, Pritchard C, Lin B, Ferguson C, Nelson PS. Isolation and characterization of the murine prostate short-chain dehydrogenase/reductase 1 (Psdr1) gene, a new member of the short-chain steroid dehydrogenase/reductase family. Gene. 2002 Jun 26;293(1-2):149-60. PubMed PMID: 12137953.

Moore SM, Nelson PS. Gene expression profiling of the human prostate androgen response program. J Androl. 2002 Mar-Apr;23(2):163-9. Review. PubMed PMID: 11868806.

Morrissey C, True LD, Roudier MP, Coleman IM, Hawley S, Nelson PS, Coleman R, Wang YC, Corey E, Lange PH, Higano CS, Vessella RL. Differential expression of angiogenesis associated genes in prostate cancer bone, liver and lymph node metastases. Clin Exp Metastasis. 2008;25(4):377-88. Epub 2007 Oct 31. PubMed PMID: 17972146.

Mostaghel EA, Montgomery B, Nelson PS. Castration-resistant prostate cancer: Targeting androgen metabolic pathways in recurrent disease. Urol Oncol. 2009 May-Jun;27(3):251-7. PubMed PMID: 19414113.

Mostaghel EA, Nelson PS. Intracrine androgen metabolism in prostate cancer progression: mechanisms of castration resistance and therapeutic implications. Best Pract Res Clin Endocrinol Metab. 2008 Apr;22(2):243-58. Review. PubMed PMID: 18471783.

Mostaghel EA, Page ST, Lin DW, Fazli L, Coleman IM, True LD, Knudsen B, Hess  DL, Nelson CC, Matsumoto AM, Bremner WJ, Gleave ME, Nelson PS. Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer. Cancer Res. 2007 May 15;67(10):5033-41. PubMed PMID: 17510436.

Nelson PS, Bourgeois KM, Nicotri T Jr, Chiu ES, Poole JC. Sclerosing sweat duct carcinoma in a 6-year-old African American child. Pediatr Dermatol. 2008 Jan-Feb;25(1):38-42. Review. PubMed PMID: 18304151.

Nelson PS, Clegg N, Arnold H, Ferguson C, Bonham M, White J, Hood L, Lin B. The program of androgen-responsive genes in neoplastic prostate epithelium. Proc  Natl Acad Sci U S A. 2002 Sep 3;99(18):11890-5. Epub 2002 Aug 16. PubMed PMID: 12185249.

Nelson PS, Clegg N, Eroglu B, Hawkins V, Bumgarner R, Smith T, Hood L. The prostate expression database (PEDB): status and enhancements in 2000. Nucleic Acids Res. 2000 Jan 1;28(1):212-3. PubMed PMID: 10592228.

Nelson PS, Gan L, Ferguson C, Moss P, Gelinas R, Hood L, Wang K. Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3114-9. PubMed PMID: 10077646.

Nelson PS, Gleason TP, Brawer MK. Chemoprevention for prostatic intraepithelial neoplasia. Eur Urol. 1996;30(2):269-78. Review. PubMed PMID: 8875211.

Nelson PS, Han D, Rochon Y, Corthals GL, Lin B, Monson A, Nguyen V, Franza BR, Plymate SR, Aebersold R, Hood L. Comprehensive analyses of prostate gene expression: convergence of expressed sequence tag databases, transcript profiling and proteomics. Electrophoresis. 2000 May;21(9):1823-31. PubMed PMID: 10870968.

Nelson PS, Hawkins V, Schummer M, Bumgarner R, Ng WL, Ideker T, Ferguson C,  Hood L. Negative selection: a method for obtaining low-abundance cDNAs using high-density cDNA clone arrays. Genet Anal. 1999 Dec 15;15(6):209-15. PubMed PMID: 10609756.

Nelson PS, Montgomery B. Cell type-specific analyses for identifying prostate cancer biomarkers. Curr Urol Rep. 2006 Jan;7(1):57-63. Review. PubMed PMID: 16480670.

Nelson PS, Montgomery B. Unconventional therapy for prostate cancer: good, bad or questionable? Nat Rev Cancer. 2003 Nov;3(11):845-58. Review. PubMed PMID:  14668815.

Nelson PS, Ng WL, Schummer M, True LD, Liu AY, Bumgarner RE, Ferguson C, Dimak A, Hood L. An expressed-sequence-tag database of the human prostate: sequence analysis of 1168 cDNA clones. Genomics. 1998 Jan 1;47(1):12-25. PubMed PMID: 9465292.

Nelson PS, Papas TS, Schweinfest CW. Restriction endonuclease cleavage of 5-methyl-deoxycytosine hemimethylated DNA at high enzyme-to-substrate ratios. Nucleic Acids Res. 1993 Feb 11;21(3):681-6. PubMed PMID: 8441677.

Nelson PS, Plymate SR, Wang K, True LD, Ware JL, Gan L, Liu AY, Hood L. Hevin, an antiadhesive extracellular matrix protein, is down-regulated in metastatic prostate adenocarcinoma. Cancer Res. 1998 Jan 15;58(2):232-6. PubMed PMID: 9443398.

Nelson PS, Pritchard C, Abbott D, Clegg N. The human (PEDB) and mouse (mPEDB) Prostate Expression Databases. Nucleic Acids Res. 2002 Jan 1;30(1):218-20. PubMed PMID: 11752298.

Nelson PS, Stanford JL, Ostrander EA. Prostate cancer research in the post-genome era. Epidemiol Rev. 2001;23(1):187-90. Review. PubMed PMID: 11588847.

Nelson PS. Identifying immunotherapeutic targets for prostate carcinoma through the analysis of gene expression profiles. Ann N Y Acad Sci. 2002 Dec;975:232-46. Review. PubMed PMID: 12538168.

Nelson PS. Predicting prostate cancer behavior using transcript profiles. J Urol. 2004 Nov;172(5 Pt 2):S28-32; discussion S33. Review. PubMed PMID: 15535439.

Page ST, Lin DW, Mostaghel EA, Hess DL, True LD, Amory JK, Nelson PS, Matsumoto AM, Bremner WJ. Persistent intraprostatic androgen concentrations after medical castration in healthy men. J Clin Endocrinol Metab. 2006 Oct;91(10):3850-6. Epub 2006 Aug 1. PubMed PMID: 16882745.

Page ST, Plymate SR, Bremner WJ, Matsumoto AM, Hess DL, Lin DW, Amory JK, Nelson PS, Wu JD. Effect of medical castration on CD4+ CD25+ T cells, CD8+ T cell IFN-gamma expression, and NK cells: a physiological role for testosterone and/or  its metabolites. Am J Physiol Endocrinol Metab. 2006 May;290(5):E856-63. Epub 2005 Dec 13. PubMed PMID: 16352669.

Pascal LE, True LD, Campbell DS, Deutsch EW, Risk M, Coleman IM, Eichner LJ,  Nelson PS, Liu AY. Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate. BMC Genomics. 2008 May 23;9:246. PubMed PMID: 18501003.

Penson DF, Albertsen PC, Nelson PS, Barry M, Stanford JL. Determining cause of death in prostate cancer: are death certificates valid? J Natl Cancer Inst. 2001 Dec 5;93(23):1822-3. PubMed PMID: 11734600.

Plymate SR, Haugk KH, Sprenger CC, Nelson PS, Tennant MK, Zhang Y, Oberley LW, Zhong W, Drivdahl R, Oberley TD. Increased manganese superoxide dismutase (SOD-2) is part of the mechanism for prostate tumor suppression by Mac25/insulin-like growth factor binding-protein-related protein-1. Oncogene. 2003 Feb 20;22(7):1024-34. PubMed PMID: 12592389.

Plymate SR, Tennant MK, Culp SH, Woodke L, Marcelli M, Colman I, Nelson PS, Carroll JM, Roberts CT Jr, Ware JL. Androgen receptor (AR) expression in AR-negative prostate cancer cells results in differential effects of DHT and IGF-I on proliferation and AR activity between localized and metastatic tumors. Prostate. 2004 Nov 1;61(3):276-90. PubMed PMID: 15368471.

Pritchard C, Coil D, Hawley S, Hsu L, Nelson PS. The contributions of normal  variation and genetic background to mammalian gene expression. Genome Biol. 2006;7(3):R26. Epub 2006 Mar 31. PubMed PMID: 16584536.

Pritchard C, Mecham B, Dumpit R, Coleman I, Bhattacharjee M, Chen Q, Sikes RA, Nelson PS. Conserved gene expression programs integrate mammalian prostate development and tumorigenesis. Cancer Res. 2009 Mar 1;69(5):1739-47. Epub 2009 Feb 17. PubMed PMID: 19223557.

Pritchard CC, Hsu L, Delrow J, Nelson PS. Project normal: defining normal variance in mouse gene expression. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13266-71. PubMed PMID: 11698685.

Pritchard CC, Nelson PS. Gene expression profiling in the developing prostate. Differentiation. 2008 Jul;76(6):624-40. Epub 2008 May 7. Review. PubMed PMID: 18462436.

Qian DZ, Huang CY, O’Brien CA, Coleman IM, Garzotto M, True LD, Higano CS, Vessella R, Lange PH, Nelson PS, Beer TM. Prostate cancer-associated gene expression alterations determined from needle biopsies. Clin Cancer Res. 2009 May 1;15(9):3135-42. Epub 2009 Apr 14. PubMed PMID: 19366833.

Schummer M, Ng W, Nelson PS, Bumgarner RE, Hood L. Inexpensive handheld device for the construction of high-density nucleic acid arrays. Biotechniques. 1997 Dec;23(6):1087-92. PubMed PMID: 9421641.

Schummer M, Ng WV, Bumgarner RE, Nelson PS, Schummer B, Bednarski DW, Hassell L, Baldwin RL, Karlan BY, Hood L. Comparative hybridization of an array of 21,500 ovarian cDNAs for the discovery of genes overexpressed in ovarian carcinomas. Gene. 1999 Oct 1;238(2):375-85. PubMed PMID: 10570965.

Schuster JM, Longo M, Nelson PS. Differential expression of bikunin (HAI-2/PB), a proposed mediator of glioma invasion, by demethylation treatment. J Neurooncol. 2003 Sep;64(3):219-25. PubMed PMID: 14558597.

Schuster JM, Nelson PS. Toll receptors: an expanding role in our understanding of human disease. J Leukoc Biol. 2000 Jun;67(6):767-73. Review. PubMed PMID: 10857847.

Schweinfest CW, Nelson PS, Graber MW, Demopoulos RI, Papas TS. Subtraction hybridization cDNA libraries. Methods Mol Biol. 1995;37:13-30. PubMed PMID: 7540089.

Takayama TK, McMullen BA, Nelson PS, Matsumura M, Fujikawa K. Characterization of hK4 (prostase), a prostate-specific serine protease: activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase. Biochemistry. 2001 Dec 18;40(50):15341-8. PubMed PMID: 11735417.

Tischkowitz MD, Yilmaz A, Chen LQ, Karyadi DM, Novak D, Kirchhoff T, Hamel N, Tavtigian SV, Kolb S, Bismar TA, Aloyz R, Nelson PS, Hood L, Narod SA, White KA,  Ostrander EA, Isaacs WB, Offit K, Cooney KA, Stanford JL, Foulkes WD. Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer. Cancer Lett. 2008 Oct 18;270(1):173-80. Epub 2008 Jun 20. PubMed PMID: 18571837.

True L, Coleman I, Hawley S, Huang CY, Gifford D, Coleman R, Beer TM, Gelmann E, Datta M, Mostaghel E, Knudsen B, Lange P, Vessella R, Lin D, Hood L, Nelson PS. A molecular correlate to the Gleason grading system for prostate adenocarcinoma. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10991-6. Epub 2006  Jul 7. PubMed PMID: 16829574.

True LD, Buhler K, Quinn J, Williams E, Nelson PS, Clegg N, Macoska JA, Norwood T, Liu A, Ellis W, Lange P, Vessella R. A neuroendocrine/small cell prostate carcinoma xenograft-LuCaP 49. Am J Pathol. 2002 Aug;161(2):705-15. PubMed PMID: 12163395.

Wang K, Gan L, Jeffery E, Gayle M, Gown AM, Skelly M, Nelson PS, Ng WV, Schummer M, Hood L, Mulligan J. Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray. Gene. 1999 Mar 18;229(1-2):101-8. PubMed PMID: 10095109.

Wang R, Xu J, Saramäki O, Visakorpi T, Sutherland WM, Zhou J, Sen B, Lim SD,  Mabjeesh N, Amin M, Dong JT, Petros JA, Nelson PS, Marshall FF, Zhau HE, Chung LW. PrLZ, a novel prostate-specific and androgen-responsive gene of the TPD52 family, amplified in chromosome 8q21.1 and overexpressed in human prostate cancer. Cancer Res. 2004 Mar 1;64(5):1589-94. PubMed PMID: 14996714.

Wang S, Gao J, Lei Q, Rozengurt N, Pritchard C, Jiao J, Thomas GV, Li G, Roy-Burman P, Nelson PS, Liu X, Wu H. Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer. Cancer Cell. 2003 Sep;4(3):209-21. PubMed PMID: 14522255.

Wright ME, Eng J, Sherman J, Hockenbery DM, Nelson PS, Galitski T, Aebersold  R. Identification of androgen-coregulated protein networks from the microsomes of human prostate cancer cells. Genome Biol. 2003;5(1):R4. Epub 2003 Dec 23. PubMed  PMID: 14709176.

Xu C, Graf LF, Fazli L, Coleman IM, Mauldin DE, Li D, Nelson PS, Gleave M, Plymate SR, Cox ME, Torok-Storb BJ, Knudsen BS. Regulation of global gene expression in the bone marrow microenvironment by androgen: androgen ablation increases insulin-like growth factor binding protein-5 expression. Prostate. 2007 Nov 1;67(15):1621-9. PubMed PMID: 17823924.

York TP, Plymate SR, Nelson PS, Eaves LJ, Webb HD, Ware JL. cDNA microarray analysis identifies genes induced in common by peptide growth factors and androgen in human prostate epithelial cells. Mol Carcinog. 2005 Dec;44(4):242-51. PubMed PMID: 16240454.